Sessions
Programme
5th Central European Biomedical Congress, Kraków, Poland,
May 29 – June 1, 2023, Future trends in health interventions
Venue: Auditorium Maximum, 33 Krupnicza Street, Krakow, Poland
| Monday, May 29, 2023 | ||
| 9.00 a.m. – 5.00 p.m. | Registration | |
| 9.30 – 10.30 a.m. – Medium Hall A + B | Plenary lecture | |
| Professor Gustavo Turecki PhD, MD | ||
| Douglas Hospital Research Centre, McGill Group for Suicide Studies, Montreal, Quebec, Canada | ||
| Molecular Mediators of Antidepressant Response | ||
| Chairpersons: Professor Marta Dziedzicka-Wasylewska, PhD; Agata Faron-Górecka, PhD | ||
| 10.30 – 11.15 a.m. – Medium Hall A + B | Center for New Pharmacotherapies of the Central Nervous System Diseases – CEPHARES – a new R&D division of the Maj Institute of Pharmacology | |
| Mission, opportunities, perspectives | ||
| Grzegorz Kreiner, PhD, Professor Andrzej Bojarski, PhD | ||
| Maj Institute of Pharmacology, Polish Academy of Sciences, Kraków, Poland | ||
| KAWA.SKA presentation | ||
| Jarosław Korczyński, PhD | ||
| 11.15 – 11.45 a.m. – Exhibition Room | Coffee break | |
| 11.45 – 1.15 p.m. – Medium Hall A or B | Session 1: Blood-brain barrier dysfunction in CNS disorders | Session 2: Mass spectrometry in medical sciences |
| Chairpersons: Professor Marta Dziedzicka-Wasylewska, PhD; Agata Faron-Górecka, PhD | Chairperson: Przemysław Mielczarek, PhD | |
| S. 01-1 | S. 02-1 | |
| Professor Marta Dziedzicka-Wasylewska, PhD | Professor Giuseppe Grasso, PhD | |
| Maj Institute of Pharmacology, Polish Academy of Sciences, Kraków, Poland | University of Catania, Catania, Italy | |
| Potential role of blood-brain barrier in stress resilience | The use of mass spectrometry in conformational diseases | |
| S. 01-2 | S. 02-2 | |
| Agnieszka Chocyk, PhD | Professor Vladimir Havlicek, PhD | |
| Maj Institute of Pharmacology, Polish Academy of Sciences, Kraków, Poland | Institute of Microbiology, Czech Academy of Sciences, Prague, Czech Republic | |
| Sex-specific effects of early-life stress on blood-brain barrier function and response to immune challenge in rats | Next generation infection diagnostics | |
| S. 01-3 | S. 02-3 | |
| Barbara Błasiak, PhD | Professor Anna Bodzon-Kulakowska, PhD | |
| Institute of Nuclear Physics, Polish Academy of Sciences, Kraków, Poland | AGH University of Science and Technology, Kraków, Poland | |
| MRI Contrast Agents Crossing Blood-Brain Barrier | Cholesterol and glucose analysis using the mass spectrometry imaging approach | |
| S. 02-4 | ||
| Marta Gawin, PhD | ||
| Maria Sklodowska-Curie National Research, Institute of Oncology, Gliwice, Poland | ||
| Possibilities and challenges of MALDI mass spectrometry imaging in cancer research | ||
| 1.15 – 2.45 p.m. – Medium Hall A or B | Session 3: Theranostic nanocarriers for drug delivery in central nervous system disorders | Session 4: Modern approaches in immunodiagnostics and immunotherapy |
| Chairpersons: Professor Władysław Lasoń, PhD; Professor Piotr Warszyński, PhD | Chairperson: Professor Maciej Siedlar, PhD | |
| S. 03-1 | S. 04-1 | |
| Juan Yang, PhD | Professor Gabriela Kania, PhD | |
| Process Chemistry and Functional Materials, SINTEF, Oslo, Norway | University of Zurich, Center of Experimental Rheumatology, Zurich, Switzerland | |
| Progress of Engineered nanoparticls as theranostic nanocarriers | Tale of two tubes exploring pathological mechanisms in systemic sclerosis – focus on monocytes and macrophages | |
| S. 03-2 (recorded lecture) | S. 04-2 | |
| William Louch, PhD | Proffessor Marcin Majka, PhD | |
| Oslo University Hospital, Oslo, Norway | Institute of Paediatrics, Jagiellonian University Medical College, Kraków, Poland | |
| Understanding cellular structure: function relationships with super-resolution microscopy | Future of cell-based therapeutics in the light of today’s developments | |
| S. 03-3 | S. 04-3 (recorded lecture) | |
| Krzysztof Szczepanowicz, PhD | Professor Radosław Zagożdżon, PhD | |
| Jerzy Haber Institute of Catalysis and Surface Chemistry, Polish Academy of Sciences, Kraków, Poland | Department of Clinical Immunology, Medical University of Warsaw, Poland | |
| Synthesis and characterization of polymer-based theranostic nanoparticles containing carnosic acid | New directions in chimeric antigen receptor (CAR)-based immunotherapies | |
| S. 03-4 | ||
| Danuta Jantas, PhD | ||
| Maj Institute of Pharmacology, Polish Academy of Sciences, Kraków, Poland | ||
| Biosafety and neuroprotective potency of polymer-based theranostic nanoparticles containing carnosic acid | ||
| S. 03-5 | ||
| Rugmani Meenambal, PhD | ||
| Maj Institute of Pharmacology, Polish Academy of Sciences, Kraków, Poland | ||
| Polyacrylic acid (PAA) conjugated cerium oxide nanoparticles as efficient neuroprotectants against oxidative stress-induced cell damage in human neuronal-like cells | ||
| 2.45 – 3.15 p.m. – Exhibition Room | Coffee break | |
| 3.15 – 3.30 p.m. – Large Hall A | Welcome ceremony | |
| Chairpersons: Honorary Committee & Organizing Committee | ||
| 3.30 – 4.30 p.m. – Large Hall A | Inaugural lecture | |
| Professor Véronique Deroche Gamonet PhD, HDR | ||
| Neurocentre Magendie, University of Bordeaux, Bordeaux, France | ||
| Re-conceptualizing the modeling of drug addiction in animals – a translational perspective | ||
| Chairperson: Jan Rodriguez Parkitna, PhD | ||
| 4.30 – 4.45 p.m. – Large Hall A | Promotion of the city of Krakow and the Maj Institute of Pharmacology Polish Academy of Sciences | |
| 4.45 – 5.45 p.m. – Large Hall A | Cellostrada Quintet concert | |
| 5.45 – 9.00 p.m. – Exhibition Room | Welcome party | |
| Tuesday, 30 May 2023 | ||
| 9.00 a.m. – 5.00 p.m. | Registration | |
| 9.00 – 10.30 a.m. – Medium Hall A or B | Session 5: The burden of neurodegenerative and psychiatric disorders: trends and future treatment | Session 6: Sphingolipids in health and brain diseases |
| Chairperson: Professor Katarzyna Starowicz-Bubak, PhD | Chairperson: Professor Christian P. Muller, PhD | |
| S. 05-1 | S. 06-1 | |
| Professor Aron H. Lichtman, PhD | Professor Christian P. Muller, PhD | |
| Virginia Commonwealth University, Richmond, VA, USA | Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany | |
| Turning over a new leaf: investigation of endocannabinoid regulating Enzymes in a mouse model of chemotherapy-induced pain | Sphingolipids in the brain: from memory control to psychiatric disorders | |
| S. 05-2 | S. 06-2 | |
| Professor Danilo De Gregorio, PhD | Alessandro Prinetti, PhD | |
| Vita-Salute University and San Raffaele Scientific Institute, Milan, Italy | University of Milano, Italy | |
| Therapeutic use of psychedelics in mental health | Sphingolipids orchestrating the cross-talk between different cell populations in the formation of myelin and in the repair of damaged myelin | |
| S. 05-3 | S. 06-3 | |
| Iskra Pollak Dorocic, PhD | Vittorio Maglione, PhD | |
| SciLifeLab, Stockholm University, Stockholm, Sweden | Neuromed, Pozzilli, Italy | |
| Transcriptional effects of SSRI administration on brain networks | Sphingolipid alterations in Huntington’s disease: new insights into molecular mechanisms and potential therapies | |
| 10.30 – 11.00 a.m. – Exhibition Room | Coffee break | |
| 11.00 – 11.30 a.m. – Medium Hall A + B | Polonium Fundation presentation | |
| Agnieszka Gawda | ||
| 11.30 – 12.30 p.m. – Medium Hall A + B | Plenary lecture | |
| Professor Kathryn A. Cunningham, PhD | ||
| University of Texas Medical Branch at Galveston, USA | ||
| Defining the Path to Maximize Therapeutics for Substance Use Disorders | ||
| Chairperson: Professor Władysław Lasoń, PhD | ||
| 12.30 – 1.30 p.m. – Exhibition Room | Poster session 1 | |
| 12.30 – 1.30 p.m. – Exhibition Room | Lunch break | |
| 1.30 – 3.00 p.m. – Medium Hall A or B | Session 7: Innovative nanocarriers and treatment modalities in antitumor therapy | Session 8: New targets, new ligands, new drugs: a novel approach for the treatment of the CNS pathologies |
| Chairperson: Professor Bożena Kamińska-Kaczmarek, PhD | Chairpersons: Professor Małgorzata Kajta, PhD; Agnieszka Wnuk, PhD | |
| S. 07-1 | S. 08-1 | |
| Professor Bożena Kamińska-Kaczmarek, PhD | Adib Zendedel, PhD | |
| Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warsaw, Poland | Institute of Neuroanatomy, Medical Faculty, RWTH Aachen University, Aachen, Germany | |
| Reinvigorating antitumor immunity in brain tumors with short peptides and siRNA-nanocarriers targeting the tumor microenvironment | The role of microglial-derived extracellular vesicles in the pathogenesis of traumatic spinal cord injury: implication of exosomal microRNAs | |
| S. 07-2 | S. 08-2 | |
| Professor Ling Peng, PhD | Professor Joanna Śliwowska, PhD | |
| Aix-Marseille University, Marseille, France | Poznań University of Life Sciences, Poznań, Poland | |
| Modular and adaptive dendrimer nanosystems in cancer treatment | Metabolic and reproductive dysfunctions associated with obesity and diabetes: From the womb to adulthood | |
| S. 07-3 | S. 08-3 | |
| Professor Tambet Teesalu, PhD | Agnieszka Wnuk, PhD | |
| University of Tartu, Tartu, Estonia | Maj Institute of Pharmacology, Polish Academy of Sciences, Kraków, Poland | |
| Targeting of nanoparticles with homing peptides | Emerging evidence for triclocarban as a neurodevelopmental risk factor: disruption of epigenetic status and dysregulation of neurogenesis-related genes | |
| S. 08-4 | ||
| Professor Małgorzata Kajta, PhD | ||
| Maj Institute of Pharmacology, Polish Academy of Sciences, Kraków, Poland | ||
| New treatment strategies against neural degenerations based on selective targeting of membrane estrogen receptors and PPARγ | ||
| 3.00 – 3.30 p.m. – Exhibition Room | Coffee break | |
| 3.30 – 5.00 p.m. – Medium Hall A or B | Session 9: Chaperons in Gaucher’s disease | Session 10: Tracking brain projections and cell signaling involved in neuroadaptations triggered by cocaine, stress, or neurodegeneration |
| Chairperson: Professor Beata Kieć-Wilk, PhD | Chairpersons: Grzegorz Kreiner, PhD; Agnieszka Zelek-Molik, PhD | |
| S. 09-1 | S. 10-1 | |
| Christine Serratice, PhD, MD | Rachel J. Smith, PhD (recorded lecture) | |
| Department of Internal Medicine, Geneva University Hospital, Geneva, Switzerland | Texas A&M University, USA | |
| Current treatment options and novel strategies for lysosomal storage disorder, like Gaucher disease | Investigating the link between habitual cocaine seeking and punishment resistance in rat models of addiction | |
| S. 09-2 | S. 10-2 | |
| Professor Mia Horowitz, PhD | Yonatan Kupchik | |
| Schmunis School of Biomedicine and Cancer Research, Tel Aviv University, Tel Aviv, Israel | The Institute for Medical Research Israel-Canada (IMRIC), The Hebrew University of Jerusalem, Israel | |
| Chaperone as a therapeutic modality in Gaucher disease | Multimodal differences between projections of the ventral pallidum and relevance to cocaine reward | |
| S. 09-3 | S. 10-3 | |
| Professor Ari Zimran, PhD, MD | Agnieszka Zelek-Molik, PhD | |
| Gaucher Unit, Shaare Zedek Medical Center, Jerusalem, Israel; Faculty of Medicine, Hebrew University, Jerusalem, Israel | Maj Institute of Pharmacology, Polish Academy of Sciences, Kraków | |
| Chaperone treatment option in neuronopathic GD and GBA related Parkinson | Psychosocial crowding stress affects neuroplasticity-related signalling pathways within rats’ frontal cortex in a region-dependent manner | |
| S.10-4 | ||
| Justyna Barut, MSc | ||
| Maj Institute of Pharmacology, Polish Academy of Sciences, Kraków, Poland | ||
| Utilization of conditional single lentivirus CRISPR/Cas9 vector for efficient gene knockout generation in adult neurons in vivo and in vitro as potential new model for study prodromal phase of Parkinson’s disease | ||
| Wednesday, 31 May 2023 | ||
| 9.00 a.m. – 5.00 p.m. | Registration | |
| 9.00 – 10.30 a.m. – Medium Hall A or B | Session 11: Medical biotechnology in disease modelling, drug research and therapy | Session 12: Novel rapid-acting antidepressants |
| Chairpersons: Professor Józef Dulak, PhD; Professor Agnieszka Łoboda, PhD | Chairpersons: Bernadeta Szewczyk, PhD; Professor Andrzej Pilc, PhD | |
| S. 11-1 | S. 12-1 | |
| Professor Józef Dulak, PhD | Professor Jeffrey M Witkin, PhD | |
| Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Kraków, Poland | University of Wisconsin – Milwaukee, USA | |
| Stem cells in neurological diseases modelling and therapies: possibilities, hopes and hypes | New age antidepressants create new ways to think about treatment | |
| S. 11-2 | S. 12-2 | |
| Florence Rage, PhD | Professor Laura Musazzi, PhD | |
| Institute de Genetique Moleculaire, CNRS, Montpellier, France | School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy | |
| From NMJ on a single chip to a Simplified Miniature Arrays (SMA) for drugs screening | Molecular signature of ketamine – response/non-response in a preclinical model of depression | |
| S. 11-3 | S. 12-3 | |
| Sifeng Chen, PhD | Professor Shigeyuki Chaki, PhD | |
| Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai, People’s Republic of China | Taisho Pharmaceutical, Japan | |
| The therapeutic effects of induced pluripotent stem cells and their exosomes on cardiovascular diseases | Ketamine-like antidepressant potential of mGlu2/3 receptor antagonists and progress of other candidates targeting the glutamatergic system | |
| 10.30 – 11.00 a.m. – Exhibition Room | Coffee break | |
| 11.00 – 11.30 a.m. – Medium Hall A + B | Celon Pharma S.A. presentation | |
| Mikołaj Matłoka, PhD; Filip Mituła, PhD | ||
| 11.30 – 12.30 p.m. – Medium Hall A + B | Plenary lecture | |
| Professsor Stefan Chłopicki, PhD, MD | ||
| Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Krakow, Poland | ||
| Endothelial biomedicine and experimental pharmacology of endothelial dysfunction; a call for endothelium-guided diagnosis and therapy | ||
| Chairperson: Professor Joanna Pera, MD, PhD | ||
| 12.30 – 1.30 p.m. – Exhibition Room | Poster session 2 | |
| 12.30 – 1.30 p.m. – Exhibition Room | Lunch break | |
| 1.30 – 3.00 p.m. – Medium Hall A or B | Session 13: Digital medicine – beyond diagnostics | Session 14: Duchenne muscular dystrophy and its complications – new tools and mechanisms for possible treatments |
| Chairperson: Klaudia Proniewska, PhD | Chairpersons: Professor Agnieszka Łoboda, PhD; Professor Józef Dulak, PhD | |
| S. 13-1 | S. 14-1 | |
| Klaudia Proniewska, PhD | Maurilio Sampaolesi, PhD | |
| Jagiellonian University Medical College, Kraków, Poland | KU Leuven, Leuven, Belgium | |
| Medical 3D cardiac anatomy supported by Mixed Reality | Harnessing novel 3D stem cell-based models to challenge dystrophic cardiomyopathy | |
| S. 13-2 | S. 14-2 | |
| Danila Potyagaylo | Jacek Stępniewski | |
| EPIQure GmbH, Nuremberg, Germany | Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Kraków, Poland | |
| Novel Ways of Bringing Non-Invasive ECG Imaging into Clinical Practice | Human induced pluripotent stem cells and gene editing for modelling of Duchenne muscular dystrophy- associated cardiomyopathy | |
| S. 13-3 | S. 14-3 | |
| Peter van Dam | Professor Agnieszka Łoboda, PhD | |
| UMC Utrecht, Utrecht, the Netherlands | Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Kraków, Poland | |
| The ventricular cineECG during acute Ischemia | Hydrogen sulfide donors: therapeutic potential in Duchenne muscular dystrophy | |
| S. 13-4 | ||
| Professor Wiesław Nowiński, PhD | ||
| Sano Centre for Computational Personalised Medicine, Krakow, Poland | ||
| Future trends in human brain atlasing | ||
| 3.00 – 3.30 p.m. – Exhibition Room | Coffee break | |
| 3.30 – 5.00 p.m. – Medium Hall A + B | Session 15: Future therapies with psychedelics | |
| Chairperson: Professor Krystyna Gołembiowska, PhD | ||
| S. 15-1 | ||
| Professor Charles Nichols, PhD | ||
| LSU Health Sciences Center, New Orleans, LA, USA | ||
| Psychedelics can produce persistent antidepressant-like effects, and changes in functional plasticity across several types of depression models | ||
| S. 15-2 | ||
| Urszula Kozłowska, PhD | ||
| Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznań, Poland | ||
| Psychedelics immunomodulatory effect on microglia and its prospect meaning for neurodegenerative diseases treatment | ||
| 8.00 – 11.00 p.m. | Congress dinner – Kościuszko Mound in Kraków, 1 Washington Avenue | |
| Thursday, 1 June 2023 | |
| 9.00 a.m. – 2.00 p.m. | Registration |
| 9.00 – 10.00 a.m. – Medium Hall A + B | Plenary lecture |
| Professor Stéphane Oliet, PhD | |
| Neurocentre Magendie, University of Bordeaux, Bordeaux, France | |
| Astroglial contribution to NMDA receptor activity | |
| Chairperson: Katarzyna Głombik, PhD | |
| 10.00 – 11.00 a.m. – Medium Hall A + B | Session 16: ERC presentation – A way to consolidate your research independence – presentations from successful ERC grant applicants |
| Chairperson: Janka Matrai, PhD | |
| European Research Council Executive Agency, Brussels, Belgium | |
| S. 16-1 | |
| Professor Ewa Chrostek, PhD | |
| Jagiellonian University, Kraków, Poland | |
| S. 16-2 | |
| Krzysztof Szade, PhD | |
| Jagiellonian University, Kraków, Poland | |
| 11.00 – 11.30 a.m. – Exhibition Room | Coffee break |
| 11.30 – 1.00 p.m. – Medium Hall A + B | Session 17: Magnificent Seven: on the role of the 5-HT7 receptor in the brain |
| Chairpersons: Monika Bijata, PhD, Professor Paweł Zajdel, PhD | |
| S. 17-1 | |
| Séverine Morisset-Lopez, PhD | |
| Center for Molecular Biophysics, CNRS, Orléans, France | |
| Discovery of biased ligands of 5-HT7R to illuminate the receptor biology | |
| S. 17-2 | |
| Professor Evgeni Ponimaskin, PhD | |
| Hannover Medical School, Hannover, Germany | |
| Targeting the serotonin receptor 7 (5-HT7R) ameliorates Tau pathology and memory deficits | |
| S. 17-3 | |
| Professor Jakub Włodarczyk, PhD | |
| Nencki Institute of Experimental Biology of Polish Academy of Science, Warsaw, Poland | |
| The molecular fingerprint of stress resilience | |
| 1.00 -1.30 p.m. – Exhibition Room | Coffee break |
| 1.30 – 2.45 p.m. – Medium Hall A + B | Session 18: Young scientific investigators’ session |
| Chairperson: Professor Agnieszka Łoboda, PhD, Professor Rafał Ryguła, PhD | |
| 2:45 – 3.15 p.m. – Medium Hall A + B | Centre for the Development of Therapies for Civilization and Age-Related Diseases (CDT-CARD) – a new R&D division of the Jagiellonian University Medical College |
| Mission, opportunities, perspectives | |
| Paweł Link-Lenczowski, PhD, Bartosz Pomierny, PhD, Tadeusz Karcz, PhD | |
| Jagiellonian University Medical College, Kraków, Poland | |
| 3.15 – 3.30 p.m. – Medium Hall A + B | Closing & Award ceremony – Medium Hall |